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National Library of Medicine

Current Bibliographies in Medicine 97-6


Introduction

ACUPUNCTURE

This bibliography was prepared in support of the National Institutes of Health (NIH) Consensus Development Conference on Acupuncture held in Bethesda, MD on November 3-5, 1997. This document was prepared by staff at the National Institute on Drug Abuse (NIDA) and the National Library of Medicine (NLM), primarily to facilitate deliberations of the consensus development panel assembled by the Office of Medical Applications of Research (OMAR) and the Office of Alternative Medicine (OAM). The authors are mindful that this document may also serve as a primary bibliographic resource for American physicians and acupuncturists, as well as the English-speaking public around the world. With this in mind, searches were conducted with several accessible computerized databases using a multi-pronged search strategy that aspired to being comprehensive in an attempt to find clinical data relevant to the use of acupuncture points. In addition, the entire NLM collection of journals on the subject of acupuncture, not otherwise indexed and with English-language articles or summaries (Table I), was hand-searched by a medical epidemiologist for articles with relevant clinical data.

TABLE I ACUPUNCTURE JOURNALS HAND SEARCHED

Acupuncture (vol. 1, 1990)
California Journal of Oriental Medicine (Spec Ed 1996)
Giornale Italiano di Riflessoterapia ed Agopuntura (Anno 1, 1989 - Anno 8, no.1, 1996)
International Journal of Veterinary Medicine (vol. 3, 1992 - vol. 6, 1995)
Needle (vol. 4, 1985 - vol. 6, 1987)
Pacific Journal of Oriental Medicine (no. 1, 1993 - no. 4, 1994 and no. 9 [c1996])
Revue Francais d'Acupuncture (vol. 6, 1980 - vol. 23, no. 90, 1997)
Washington Update of Acupuncture (vol 2, no. 1-7, 1997)
World Journal of Acupuncture (vol. 1, 1991 - vol. 2, 1992)

This bibliography has also incorporated much of the previous efforts and the organizational strategy of the Medical Acupuncture Research Foundation (MARF) bibliographies, compiled primarily by Russell J. Erickson, MD, and disseminated by the American Academy of Medical Acupuncture (AAMA)*. Most of the MARF topic sections have been further subdivided into sub-sections labeled "selected controlled trials" (Section A) and "other data" (Section B). Computer-indexed articles with descriptors including the terms "random" and/or "blind" (or variations thereof) were included in section A, along with hand-searched articles thought by the epidemiologist/searcher to be particularly useful controlled trials. While many excellent trials and useful case-series may have been included in section B, the clinician looking for the quickest and most definitive answers will usually be able to find many of the most important articles in section A. This bibliography includes citations indexed from January 1970 through September 1997. For ongoing acupuncture citations after these dates, the electronic databases listed in Table II will be very useful for the English-speaking clinician/researcher. Another resource that may be useful in the future is ACULARS, the Acupuncture Literature Analysis and Retrieval System, produced by the Beijing Institute of Information and Library of the Academy of Traditional Chinese Medicine in Beijing. That database was not utilized for this bibliography because of its cost and the consideration that most of the information in ACULARS is not yet available in English.

TABLE II DATABASES

Databases found to contain numerous unique bibliographic references:

Allied and Alternative Medicine produced by the British Library, Yorkshire, U.K.
EMBASE® (formerly Excerpta Medica) produced by Elsevier Science B.V., Amsterdam
Manual, Alternative and Natural Therapy
TM (MANTISTM) produced by Action Potential, Inc., Denton, TX
MEDLINE® produced by the National Library of Medicine, Bethesda, MD

Additional databases useful for veterinary literature:

AGRICOLA produced by the National Agricultural Library, Beltsville, MD
CAB ABSTRACTS produced by CAB International, Wallingford, U.K.

For the purposes of this conference, the term 'acupuncture' has been defined as "stimulation, primarily by the use of solid needles, of traditionally and clinically defined points on and beneath the skin, in an organized fashion for therapeutic and/or preventive purposes." The original acupuncture points (or "acupoints") are specific superficial anatomic locations defined in traditional Asian texts. The skin on or over these points is generally lower in transdermal electrical resistance than the skin surrounding them. There is considerable overlap between these traditional acupoints and points defined by other means in modern physical medicine such as "trigger points," "motor points," or "osteopathic lesions" (among other terms). These points are often palpable subcutaneously as either mild depressions or small and sometimes tender nodules. In traditional Asian medicine these points are stimulated either by puncture and manual manipulation of solid needles or by local heating. Heating is generally accomplished by the burning of dried, powdered Artemisia vulgaris (moxa), referred to as "moxibustion." This moxa is either placed or held just above the acupoint by the acupuncturist (indirect moxibustion), attached to a needle penetrating the point, or applied directly to the skin (direct moxibustion, generally removed prior to causing any detectable skin-burn). In modern times, additional methods of stimulating the acupoints include applications of electric current to needles in the points or skin electrodes over the points, injections into the points, laser-light directed onto the points, or finger-pressure massage of selected points, called "acupressure." In addition, many new points and whole new systems of points have been described on specific body-parts, leading to (for instance) scalp-acupuncture, hand-acupuncture, and ear-acupuncture.

What combination of acupoints are the best points to stimulate in which ways for various clinical problems has been the subject of writing and argument for centuries. Different systems and approaches are associated with various schools of thought and national traditions in Asia and the West. Acupuncture practitioners in European countries such as France, Italy, Germany, and England have evolved their own approaches to the clinical use of acupuncture points in the past century. Some of these are based on approaches popular at different times and places in Asian history, or based on diverse interpretations of traditional Chinese texts, or on different syntheses of material from these texts with the modern information derived from neurology, physiology, information theory, and biophysics. Much of the clinical literature of acupuncture is concerned with descriptions of these various approaches to clinical problems based on different theories or schools of thought. Most of that literature has not been included in this bibliography. While some historical or conceptual pieces have been included for the sake of completeness, the main purpose of this bibliography has been to compile citations of articles containing actual clinical data from defined numbers of human or animal subjects, to help answer the question of whether or not acupoint stimulation had a detectable and useful effect as performed in that particular study.

An acupuncture treatment is a procedure, like surgery or a psychotherapy session, rather than a drug. For this reason it has been very difficult to subject acupuncture to the gold-standard of randomized blinded trials (RBTs), and almost impossible to conduct truly double-blind trials. Much of the clinical data available for acupuncture consists of case-series, such as those often reported for new surgical procedures. For areas in which many RBTs are available (such as the prevention and treatment of nausea and vomiting), these RBTs are the articles that have been emphasized in this collection. For areas in which fewer such definitive trials are available, a greater emphasis has been placed on including large case-series or other sources of less definitive, but still potentially useful clinical data. In addition, every attempt has been made to include the most complete possible list of "side effects" and other adverse events that have been reported in association with acupuncture. This may have resulted in the inclusion of multiple descriptions of single adverse events as well as the probable inclusion of events in which acupuncture was only one of many interventions being used and may not have been the cause of the "side effect."

This bibliography has been assembled specifically to help answer the question of whether, based on the clinical data, acupuncture point therapy is likely to be helpful in a given clinical problem. It is dedicated to the patients, clinicians, and researchers who have produced the information indexed here, as well as to the patients who may benefit from this information in the future. The authors would like to thank Adam Glazer, Jennie P. Hunt, and Peggie S. Tillman of the NLM for their assistance.

Any reproductions of this bibliography, in whole or in part, must include all credits. If you wish to cite this bibliography, the correct format is:
Klein, Lori J.; Trachtenberg, Alan I., compilers. Acupuncture [bibliography online]. Bethesda (MD): National Library of Medicine; 1997 Oct [insert cited year month day in brackets]. [insert no. of screens or lines in brackets]. (Current bibliographies in medicine; no. 97-6). 2302 citations from January 1970 through October 1997. Available from: URL http://www.nlm.nih.gov/pubs/resources.html

* American Academy of Medical Acupuncture
Medical Acupuncture Research Foundation
5820 Wilshire Blvd. Suite 500
Los Angeles CA 90036
213-937-5514 or 800-521-2262 Fax: 213-937-0959
MARF website: www.medicalacupuncture.org

Information resource: http://www.nlm.nih.gov/pubs/cbm/acupuncture.html#115


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